主要从事高性能光学染料的前沿基础和生物医学应用研究，创制了系列高性能荧光染料和光学探针应用于成像检测。目前以第一作者或共同第一作者身份在Angew. Chem. Int. Ed., Anal. Chem., Coord. Chem. Rev., Chem. Commun., Sens. Actuators B Chem., Dyes Pigments等期刊发表论文多篇。

2012.9-2016.6 湖南科技学院，理学学士

2016.9-2019.6 中南大学，理学硕士

2019.9-2023.6 湖南大学，理学博士

2023.6-至今 湖南科技大学，讲师

[1] 国家自然科学青年基金项目(30万)，2025年-2027年

[2] 湖南科技大学博士启动基金(10万)

[3]湖南省自然科学基金面上项目（5万），2026年-2028年

1. Long He, Lin-Hui He, Shuai Xu, Tian-Bing Ren*, Xing-Xing Zhang, Zuo-Jia Qin, Xiao-Bing Zhang, Lin Yuan*. Engineering of reversible NIR-II redox-responsive fluorescent probes for imaging of inflammation in vivo. Angew. Chem. Int. Ed., 2022, 61, e202211409.

2. Long He, Yi Li, Chonghua Zhang, Xingxing Zhang*, Benhua Wang, Tianbing Ren*, Lin Yuan.Development of small-molecule NIR-II photothermal agents for image-guided tumor therapy. Coord. Chem. Rev., 2025, 533, 216549.

3. Long He, Hang Li, Yao Tang, Tian-Bing Ren*, Lin Yuan. Recent advances in fluorescent probes for fatty liver imaging by detecting lipid droplets. J. Mater. Chem. B, 2024, 12, 10149.

4. Long He^#, Jing Huang^#,Xingxing Zhang, Tian-Bing Ren*, Lin Yuan*. Asymmetric π-extension design of long wavelength rhodamine derivatives for imaging and phototherapy. ChemPhotoChem. 2024, 8, e202400191.

5. Jing Huang^#, Long He^#, Jiaoliang Wang*, Junchao Xu*, Lin Yuan*. Near-infrared hemicyanine fluorophores with optically tunable groups: A ‘leap forward’ for in vivo sensing and imaging. Synlett, 2024, 35, 21-28.

6. Long He, Lin-Hui He, Huan-Hua Lai, Shuai Xu*, Jiao-Liang Wang, Jun-Chao Xu, Ling Shi*, Lin Yuan. Synergistic phototherapy of NIR wavelength xanthene-quinoline salt-based heavy-atom-free photosensitizers for tumor therapy. Chem. Commun., 2023, 59, 10745-10748.

7. Long He, Haiqing Xiong, Benhua Wang, Yun Zhang, Jingpei Wang, Hongyan Zhang*, Haipu Li, Zhaoguang Yang, Xiangzhi Song*, Rational design of a two-photon ratiometric fluorescent probe for hypochlorous acid with a large Stokes shift. Anal. Chem., 2020, 92, 11029-11034.

8. Long He, Yun Zhang, Haiqing Xiong, Jingpei Wang, Yani Geng, Benhua Wang, Yangang Wang, Zhaoguang Yang, Xiangzhi Song*. A ratiometric flavone-based fluorescent probe for hypochlorous acid detection with large Stokes shift and long-wavelength emission. Dyes Pigments, 2019, 166, 390-394.

9. Long He, Xingjiang Liu, Yun Zhang, Lei Yang, Qian Fang, Yani Geng, Wenqiang Chen*, Xiangzhi Song*. A mitochondria-targeting ratiometric fluorescent probe for imaging hydrogen peroxide with long-wavelength emission and large Stokes shift. Sens. Actuat. B Chem., 2018, 276, 247-253.

10. Xingjiang Liu^#, Long He^#, Liu Yang, Yani Geng, Lei Yang, Xiangzhi Song*. Iminocoumarin-based fluorescence probe for intracellular H₂O₂ detection with a red emission and a large Stokes shift. Sens. Actuat. B Chem., 2018, 259, 803-808.

功能小分子荧光染料及探针的设计合成、生物传感与成像