李毅

  • 性 别:
  • 职称:副教授
  • 学 历:博士研究生
  • 学院:化学化工学院
  • 系部所:教育部重点实验室
  • 执教层次:博士生导师
  • 电话:
  • 电子邮箱:yli@hnust.edu.cn

基本情况

李毅,男,1986年9月出生,博士,副教授,博士研究生导师。2014年博士毕业于中山大学。湖南科技大学“奋进学者”(青年创新人才)。主要研究方向为过渡金属配合物的抗肿瘤及生物成像研究。近年来,先后共主持国家自然科学基金,湖南省自然科学基金,中国博士后基金等项目。在Biomaterials、Chemical Science、Chemical Communications、Sensors and Actuators B: Chemical、Dalton Transactions等重要学术期刊上发表论文20余篇,论文被引1000余次。

学习经历

2005年09月—2009年06月 吉首大学,学士

2009年09月—2014年12月 中山大学(硕博连读),博士

工作经历

2015年01月—2017年07月 中山大学中山医学院,博士后

2017年07月—2018年12月 湖南科技大学

2018年12月—至今  湖南科技大学,副教授

承担课程

《无机化学》《普通化学》《无机化学实验》

主持课题

[1] 国家自然科学基金青年基金,21601210,2017.01-2019.12,主持。

[2] 湖南省自然科学基金,2019JJ50188,2019.01-2021.12,主持。

[3] 中国博士后科学基金,2015M572397,2015.01-2016.12,主持。

代表性论文

[1] Ben Liu, Jing Long, Meng Zhang, Kaiming Cheng, Xin Gao, Yibo Zhou, Yi Li *, Zilong Tang*, Wei Zhang*. Mitochondria-targeted phosphorescent cyclometalated iridium(III) complex for bioimaging of H2S. J. Inorg. Biochem., 2022, 226, 111626.

[2] Xiang-Fu Du#, Yi Li # (共同第一作者), Jing Long, Wei Zhang?, Dou Wang, Cai-Rong Li , Mei-Xia Zhao?, Yuxiao Lai,? Fabrication of cisplatin-loaded polydopamine nanoparticles via supramolecular self-assembly for photoacoustic imaging guided chemo-photothermal cancer therapy. Appl. Mater. Today 2021, 23, 101019.

[3] Wei Zhang,# Yi Li# (共同第一作者), Lanju Xu,? Dou Wang, Jing Long, Meng Zhang, Yufei Wang, Yuxiao Lai* and Xing-Jie Liang.* Near-Infrared-Absorbing Conjugated Polymer Nanoparticles Loaded with Doxorubicin for Combinatorial Photothermal- Chemotherapy of Cancer. ACS Appl. Polym. Mater. 2020, 2, 4180?4187.

[4] Yi Li,* Ben Liu, Cui-Xia Xu, Liang He, Yi-Chao Wan, Liang-Nian Ji and Zong-Wan Mao*. Mitochondria-targeted phosphorescent cyclometalated iridium(III) complexes: Synthesis, characterization and anticancer properties. J. Biol. Inorg. Chem., 2020, 25, 597-607.

[5] Yi Li, Kang-Nan Wang, Liang He, Liang-Nian Ji and Zong-Wan Mao*, Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes. J. Inorg. Biochem., 2020, 205, 110976. 

[6] Yi Li, Kang-Nan Wang, Liang He, Liang-Nian Ji and Zong-Wan Mao*, Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes.  J. Inorg. Biochem.,  2020, 205, 110976.

[7] Yi Li, Kang-Nan Wang, Bing Liu, Xin-Ran Lu, Meng-Feng Li,* Liang-Nian Ji and Zong-Wan Mao*, Mitochondria-targeted two-photon fluorescent probe for the detection of biothiols in living cells.  Sensors and Actuators B: Chemical  2018, 255, 193-202.

[8] Yi Li, Kang-Nan Wang, Bing Liu, Xin-Ran Lu, Meng-Feng Li,* Liang-Nian Ji and Zong-Wan Mao*, Cyclometalated iridium(III) N-heterocyclic carbene complexes as potential mitochondrial anticancer and photodynamic agents.  Dalton Trans ., 2017, 46, 11363-11371.

[9] Yi Li, Cai-Ping Tan, Wei Zhang, Liang He, Liang-Nian Ji and Zong-Wan Mao*, Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents.  Biomaterials  2015, 39, 95-104.

[10] Yi Li, Gao-Feng Liu,* Cai-Ping Tan, Liang-Nian Ji and Zong-Wan Mao*, Antitumor properties and mechanisms of mitochondria-targeted Ag(I) and Au(I) complexes containing N-heterocyclic carbenes derived from cyclophanes.  Metallomics  2014, 6, 1460-1468.

[11] Liang He, Yi Li, Cai-Ping Tan,* Rui-Rong Ye, Mu-He Chen, Jian-Jun Cao, Liang-Nian Ji and Zong-Wan Mao*, Cyclometalated iridium(III) complexes as lysosome targeted photodynamic anticancer and real-time tracking agents.  Chem. Sci. , 2015, 6, 5409-5418.

[12] Qian Cao, Yi Li, Eva Freisinger, Peter Z. Qin,* Roland K. O. Sigel,* and Zong-Wan Mao*, G-Quadruplex DNA Targeted Metal Complexes Acting as Potential Anticancer Drugs.  Inorg. Chem. Front.,  2017, 4, 10-32.