谷慧

  • 性 别:
  • 职称:教授
  • 学 历:博士研究生
  • 学院:化学化工学院
  • 系部所:制药工程系
  • 执教层次:博士生导师
  • 电话:
  • 电子邮箱:hgu@hnust.edu.cn

基本情况

谷慧,女,1988年生,博士,教授,玛丽居里学者。主要从事单细胞电化学分析、活体电化学分析,近年来主持国家自然科学基金、湖南省自然科学基金等9项,在《Angew. Chem. Int. Ed.》《Anal. Chem.》、《ACS sensors》、《Biosens Bioelectron》等SCI上公开发表论文20余篇。

学习经历

2006.09-2010.06,湖南师范大学,学士,制药工程

2010.09-2015.06,华东师范大学,博士,分析化学

2013.09-2014.09,美国匹兹堡大学,联合培养博士,分析化学

2022.09-2025.08,瑞典哥德堡大学,玛丽居里学者,分析化学

工作经历

2015.10-至今,湖南科技大学,教师

承担课程

《分析化学实验》

《药物分析》

《制药工程专业英语》

主持课题

1.  09/2022–08/2025, 欧盟委员会玛丽·居里人才项目,22万欧元,主持

2.     01/2025-12/2028,国家自然科学基金面上项目,50万元,主持

3.   01/2025-12/2028湖南省自然科学基金优秀青年项目20万元,主持

4.     01/2022-12/2025,湖南省线上本科课程基金资助项目,《分析化学实验》线上一流课程,主持

5.     01/2021-12/2024,湖南省线上本科课程基金资助项目,《分析化学实验》线上线下混合式一流课程,主持

6.     01/2017–12/2019, 国家自然科学基金青年项目,20万元,主持

7.     10/2019 –12/2021, 湖南省教育厅优秀青年项目,6万元,主持

8.     01/2021–12/2023,湖南省自然科学基金面上项目,5万元,主持

9.     01/2017–12/2019, 湖南省自然科学基金青年项目, 5万元,主持




代表性论文

1.       Hui Gu, Chaoyi Gu, Nicolas Locker, Andrew G. Ewing; Amperometry and Electron Microscopy show Stress Granules Induce Homotypic Fusion of Catecholamine Vesicles, Angew. Chem. Int. Ed. 2024, 3, e202400422.

2.       Yimei Zuo, Sisi Wang, Ruizhi Lin, Gelei Xiao, Shu Chen, Rongjin Zeng, Hui Gu*; A portable electrochemical microsensor for in-site measurement of dissolved oxygen and hydrogen sulfide in natural water, Talanta 2023, 256, 124269.

3.       Yu Luo; Ruizhi Lin; Yimei Zuo; Ziyi Zhang; Yi Zhuo; Ming Lu; Shu Chen; Hui Gu*; Efficient Electrochemical Microsensor for In Vivo Monitoring of H2O2 in PD Mouse Brain: Rational Design and Synthesis of Recognition Molecules, Analytical Chemistry 2022, 94(25): 9130-9139.

4.       Ziyi Zhang, Mengyin Li, Yimei Zuo, Shu Chen*, Yi Zhuo, Ming Lu, Guoyue Shi, Hui Gu*. In Vivo Monitoring of pH in Subacute PD Mouse Brains with a Ratiometric Electrochemical Microsensor Based on Poly(melamine) Films, ACS Sensors 2022, 7(1): 235-244.

5.       Chenchen Li#, Yi Zhuo#, Xia Xiao, Shuangfu Li, Kai Han*, Ming Lu, Jiaxin Zhang, Shu Chen, Hui Gu*, Facile electrochemical microbiosensor based on in situ self-assembly of Ag nanoparticles coated on Ti3C2Tx for in vivo measurements of chloride ions in the PD mouse brain, Analytical Chemistry 2021, 93, 21, 7647–7656. 

6.       Xia Xiao, Chenchen Li, Yuzhi Liu, Yaqian Feng, Kai Han, Haoyue Xiang*, Guoyue Shi, Hui Gu*,A ratiometric electrochemical microsensor for monitoring of chloride ion in vivo, Analyst 2021, 146, 6202-6210.

7.       Yimin Jiang#, Xia Xiao#, Chenchen Li, Yu Luo, Shu Chen, Guoyue Shi, Kai Han, Hui Gu*, Facile ratiometric electrochemical sensor for in vivo/online repetitive measurements of cerebral ascorbic acid in brain microdiaysate. Analytical Chemistry 2020, 92, 5: 3981–3989. (12 citations)

8.       Hui Gu*, Yanqiu Guo, Xia Xiao, Chenchen Li, Guoyue Shi, Jian He*, Double molecular recognition strategy based on boronic acid−diol and NHS ester−amine for selective electrochemical detection of  of cerebral dopamine. Analytical and Bioanalytical Chemistry 2020, 412, 3727–3736. 

9.       Hui Gu*, Qi Hou, Yu Liu, Yujie Cai, Yanqiu Guo, Haoyue Xiang, Shu Chen*, On-line regeneration of electrochemical biosensor for in vivo repetitive measurements of striatum Cu2+ under global cerebral ischemia/reperfusion events, Biosensensors Bioelectronics 2019, 135: 111–119. 

10.     Hui Gu*, Yu Liu, Tianyao Ren, Wenbiao Xia, Yanqiu Guo, Guoyue Shi, An electrochemical biosensor based on double molecular recognition for selective monitoring of cerebral dopamine dynamics at 4 min interval, Sensors Actuators B: Chemcal 2019, 287: 356–363.

11.     Hui Gu*, Yidan Xing, Ping Xiong, Huiling Tang, Chenchen Li, Shu Chen, Rongjin Zeng, Kai Han*, Guoyue Shi, Three-dimensional porous Ti3C2Tx MXene–graphene hybrid films for glucose biosensing. ACS Applied Nano Materials 2019, 2: 6537−6545. 

12.     Hui Gu*, Ping Xiong, Huiling Tang, Shu Chen, Yunfei Long, Guoyue Shi, In vivo monitoring of cerebral glucose with an updated on-line electroanalytical system. Analytical and Bioanalytical Chemistry 2019, 411, 5929–5935. 

13.     Huiling Tang, Dehao Cai, Tianyao Ren, Ping Xiong, Yu Liu, Hui Gu*,Guoyue Shi, Fabrication of a low background signal glucose biosensor with 3D network materials as the electrocatalyst. Analytical Biochemistry 2019, 567, 63–71. (11 citations)

14.     Hui Gu*, Huiling Tang, Ping Xiong, Zhihua Zhou*, Biomarkers-based Biosensing and Bioimaging with Graphene for Cancer Diagnosis. Nanomaterials 2019, 9, 130. 


研究方向

活体电分析化学