赵云辉，男，博士，副教授，硕士生导师，毕业于复旦大学化学系。参与国家自然科学基金项目多项，主持省部级课题4项和其它项目多项，指导国家级、省级大学生创新创业训练项目、大学生化学化工创新作品竞赛多项。主要从事功能分子的设计、合成及应用研究，近年来在《Chem. Commun.》、《Anal. Chim. Acta》、《Org. Chem. Front.》、《J. Org. Chem.》、《Dyes and Pigments》、《Tetrahedron Lett.》、《Synlett》等国内外重要刊物上公开发表SCI论文30余篇，为《ACS Appl. Mater. Inter.》、《Anal. Chem.》、《J. Org. Chem.》等知名刊物审稿人；授权发明专利10余项，转让5项。

承担《药物合成》和《新药研发前沿》等课程的教学工作。

1. 极性与二面角双可调型聚苯乙烯-轴手性联苯双膦配体的制备及其拆分氨基酸对映体性能研究,国家自科项目，参与；
   

2. 自示踪智能型硅质体药物载体的制备及其诊治监控一体化特性和机理，湖南省自科基金，主持

3. 基于核酸适配体与GO的粮食中汞离子检测方法研究，国家工程实验室开放课题，主持

4. 新型两亲AIE分子的合成及其在温敏材料中的应用研究，湖南省教育厅优秀青年项目，主持

5. 钐促进的稠环氮杂化合物的合成，中科院重点实验室开放课题，主持

6. 水性聚氨酯砂浆地坪涂料，企业开发项目，主持

[1] Zhao, Yunhui*; Luo, Yueyang; Liu, Jun; Zheng, Changwu*; Zhao, Gang*，Multiple Hydrogen-Bonding Catalysts Enhance the Asymmetric Cyanation of Ketimines and Aldimines，Chemistry—A European Journal, 2023, 29(e202302061): 1-6.

[2]  Guan, Meng;Hou, Ming;Tang, Shuwang; Cheng, Guang; Zhu, Xinyu; Zhao, Yun-Hui*; Tang, Ximei; Zhou, Hongwei; Qiu, Guanyinsheng*，Iron-catalyzed beta- hydroxymethylative carbonylation of styrene under photo-irradiation，Chemical Communications, 2023, 59(10.1039/d3cc03919f): 13309-13312.

[3] Guo, Tao; Hu, Penghua; Liu, Yu; Zhang, Panke*; Zhao, Yunhui*; Zhu, Congjun*，Ketosulfonylmethylenation and sulfonylethyleneation of imidazoheterocycles with dimethylformamide as a methylene source，Chemical Communications, 2023, 59(36): 12455-12458.

[4]. Tao Guo, Lei Bi, Miao Zhang, Cong-Jun Zhu,* Li-Bo Yuan,* and Yun-Hui Zhao*，Access to Sulfur-Containing Bisheterocycles through Base-Promoted Consecutive Tandem Cyclization/Sulfenylation with Elemental Sulfur，J. Org. Chem. 2022, 87, 16907−16912.

[5] 谭佳敏，余雅君，关猛，赵云辉*，唐子龙，周智华，郭涛*，基于异喹啉骨架结构的新型聚集诱导发光分子的设计与合成，有机化学， 2022, 42, 3776～3783

[6]. Y.-H. Zhao,*Y. Yu, T. Guo, Z. Zhou, Z. Tang, L. Tian, Design, synthesis and applications of fluoride probe based on aromatization of isoquinolinium salts,  Dyes and Pigments , 2020, Doi: https://doi.org/10.1016/j.dyepig.2020.108547.

[7]. T. Guo*; X.-N. Wei; M. Zhang; Y. Liu; L.-M. Zhu; Yun-Hui Zhao*; Catalyst and additive-free oxidative dual C-H sulfenylation of imidazoheterocycles with elemental sulfur using DMSO as solvent and oxidant,  Chemical Communications , 2020, 56, 5751-5754.

[8]. Y.-H. Zhao,* Y. Yu, D. Hu, L. Zhao, W. Xie, Z. Zhou, Cascade oxidation /radical addition/ annulation of  o -alkynylarylaldimine with indole/imidazopyridine: access to aromatic heterocycle-substituted isoquinolines,  Asian J. Org. Chem. , 2020, 9, 953-960.

[9].Y.-H. Zhao*, Y. Luo, H. Wang, H. Wei, T. Guo, H. Tan, L. Yuan, X.-B. Zhang, A novel ratiometric and reversible fluorescence probe with a large Stokes shift for Cu2+ based on a new clamp-on unit. Anal. Chim. Acta 2019, https://doi.org/10.1016/j.aca.2019.03.029.

[10]. T. Guo,* X.-N. Wei, Y. Liu, P.-K. Zhang and Y.-H. Zhao*, Oxidative dual C–H selenation of imidazoheterocycles with ethersor alkanes using selenium powder via a radical pathway, Org. Chem. Front., 2019, DOI: 10.1039/C9QO00198K

[11]. Y.-H. Zhao, Y. Luo, H. Wang, T. Guo*, H. Zhou, H. Tan, Z. Zhou*, Y. Long, Z. Tang, A New Fluorescent Probe Based on Aggregation Induced Emission for Selective and Quantitative Determination of Copper(II) and its Further Application to Cysteine Detection, Chemistryselect, 2018, 3, 1521-1526.

[12]. Y.-H. Zhao*, Y. Luo, Y. Zhu, H. Wang, H. Zhou, H. Tan, Z. Zhou*, Y.-C. Ma*, W. Xie, Z. Tang, Synthesis of potential anticancer 1-(1H-Indol-3-yl)-isoquinolines via AgNO3-mediated tandem reactions of 2-alkynylbenzaldehyde azines and indoles,  Synlett , 2018, 29,773-778.

[13]. T. Guo*, X.-N. Wei, H.-Y. Wang, Y.-L. Zhu, Y.-H. Zhao*, Y.-C. Ma*, Copper-catalyzed chalcogenation ofimidazoheterocycles with sulfur/selenium powderand coumarinyltriflates,  Org. Biomol. Chem.  2017, 15, 9455-9464.

[14]. Y.-H. Zhao, Y. Li, M. Luo, Z. Tang, K. Deng, AgNO3-Mediated Cyclization/N-N Bond Cleavage Reaction for the Synthesis of 3-Aryl Isoquinolines, Synlett, 2016, 27, 2597-2600;

[15]. Y.-H. Zhao, Y. Li, Y. Long, Z. Zhou, Z. Tang, K. Deng, S. Zhang, Highly selective fluorescence turn-on determination of fluoride ions via chromogenic aggregation of a silyloxy-functionalized salicylaldehyde azine, Tetrahedron Lett., 2017, 58, 1351-1355.

1. 类天然有机分子的构建及其生物活性，谢文林，赵云辉，张慧霖，于贤勇，湖南省自然科学三等奖，2021年。

2. “四协四融”培养地方高校化材类创新人才探索与实践，周智华，张少伟，郑柏树，赵云辉，方建军，等；湖南省高等教育教学成果奖三等奖，2022年。
   

曾获湖南科技大学“优秀班主任”、“教学优良榜”、“就业创业工作先进个人”等荣誉称号。

[1] 赵云辉，李余波，一种吡唑并异喹啉化合物及其合成方法，ZL201510900073.0.

[2] 赵云辉，周智华，刘立华，谢文林，唐子龙, 一种基于聚集诱导发光的温敏荧光材料及其制备方法和应用, ZL201611112262.2.

[3] 赵云辉，李余波，周智华，唐子龙，龙云飞, 一种基于聚集诱导发光的氟离子检测探针及其制备方法和应用, ZL201610969539.7.

[4] 赵云辉，周智华，刘立华，谢文林，唐子龙, 一种基于四苯乙烯的荧光化合物及其制备方法和应用, ZL201611269867.2.

[5] 赵云辉; 余雅君; 刘立华; 周智华 , 一种吲哚取代的二氢异喹啉化合物及其合成方法, ZL201910878350.0 .

[6] 赵云辉; 罗月阳; 周智华; 刘立华 ; 一种吲哚取代的异喹啉化合物及其合成方法, ZL201710753940.1

[7] 赵云辉;周智华;刘立华;唐子龙, 一种汞离子检测探针及其制备方法和应用, ZL201910050646.3

[8] 赵云辉;罗月阳;刘立华;周智华, 基于邻炔基苯并唑的铜离子检测探针及其制备方法和应用, ZL201810773338.9

现主要从事生物活性分子与功能材料的合成及应用研究