陈冠凡,男,1978年生,博士,副教授,现为中国化学会会员,分子构效关系湖南省普通高校重点实验室成员,《有机化学》湖南省精品课程成员。主要从事(1)新型荧光探针分子的设计、合成及其识别性质的研究,(2)分子结构与性能之间构效关系(QSPR)的研究。迄今为止,在SCI期刊上发表论文10余篇,其主要研究成果相继发表于《Spectrochimica Acta Part A》、《J.Mole. Struc》、《J. Phys. Org. Chem.》、《Magn. Reson. Chem.》、《J. Coord. Chem.》等国际学术期刊。主持国家自然科学基金青年项目1项,湖南省教育厅青年项目1项,理论有机化学与功能分子教育部重点实验室开放基金1项,指导本科生大学生科研创新计划(SRIP)2项。作为主要成员参与国家自然科学基金5项、湖南省自然科学基金2项、教育部青年基金1项、湖南省高校创新平台开放基金1项。
1、 国家自然科学基金,芳基多烯类席夫碱分子性能中结构因素的共同影响规律的研究(No. 21202043),25万,2013.01-2015.12
2、 湖南省教育厅青年项目,基于单羟基卟啉的硫离子荧光探针设计合成及其立体效应研究(No. 16B087),3万,2016.8-2018.12
1、Guanfan Chen, Mengzhuo Tang, Xiufang Fu,etc.A highly sensitive and selective “off-on” porphyrin-based fluorescent sensor for detection of thiophenol.J. Mol. Struct. 2019, 1179, 593-596.
2、Guanfan Chen, Mengzhuo Tang, Xiufang Fu, etc.A highly sensitive and selective fluorescent sensor for detection of sulfide anion based on the steric hindrance effect.J. Mol. Struct. 2018, 1151, 230-235.
3、Guanfan Chen, Mengzhuo Tang, Rongjin Zeng, etc, Group effect on ionization potential for mono-substituted aliphatic compounds, J. Phy. Org. Chem. 2015, 28(9), 612-616.
4、Guanfan Chen, Xiangsi Wu, Chengzhong Cao, etc, A QSPR correlation on the 13C NMR chemical shifts of bridge carbons for different series of aromatic Schiff bases. Mag. Reson. Chem., 2015, 53(2), 172-177.
5、Guanfan Chen,Chenzhong Cao,Yun Zhu,etc,The alternating of substituent effect on the 13C NMR shifts of all bridge carbons in cinnamyl aniline derivatives,Spectrochimica Acta Part A,2012,99(12),218-222.
6、Guanfan Chen ,Chenzhong Cao,Bingtao Lu ,etc. The substituent effect on the UV energy of 4,4′‐disubstituted benzylideneanilines, J. Phy. Org. Chem.2012, 25(4), 327-333.
7、Guanfan Chen ,Chenzhong Cao,Bin Sheng ,etc. Substituent effect study on δ c values of the bridge group carbons in disubstituted cinnamyl aniline series,J. Phy. Org. Chem.2012,25(10), 828-834.
8、Guanfan Chen, Chenzhong Cao, Substituent effect on the UV spectra of p‐disubstituted compounds XPh(CH="CHPh)nY" (n =" 0," 1, 2), J. Phy. Org. Chem.2010, 23(8), 776-782.
9、Chenzhong Cao, Guanfan Chen, Zhiqing Yin, Excited‐state substituent constants σ from substituted benzenes, J. Phy. Org. Chem. 2008,21(9), 808-815.
10、Chenzhong Cao ,Yun Zhu ,Guanfan Chen,Effect of substituents and conjugated chain length on the UV spectra of α,ω‐di‐substituted phenyl polyenes,J. Phy. Org. Chem. 2013,26(10),834-839
11、Zhengjun Fang ,Chenzhong Cao ,Guanfan Chen,Substituent effects on the 13C NMR chemical shifts of the imine carbon in N ‐(4‐X–benzylidene)‐4‐(4‐Y–styryl) anilines,J. Phy. Org. Chem. 2012,25(12), 1343-1350。
12、Chenzhong Cao,Bin Sheng ,Guanfan Chen,Determining the excited‐state substituent constants of meta‐substituent from 3,4'‐disubstituted stilbenes,J. Phy. Org. Chem.2012,25(10), 1315-1320.
13、Chenzhong Cao ,Bingtao Lu ,Guanfan Chen,Investigation of the substituent specific cross‐interaction effects on 13C NMR of the C="N" bridging group in substituted benzylidene anilines,J. Phy. Org. Chem. 2011,24(4), 335-341.
14、FenminCheng, XiangsiWu, MaliLiu, YunfeiLong,GuanfanChen, etc.A porphyrin-based near-infrared fluorescent sensor for sulfur ion detection and its application in living cells, Sensors and Actuators B: Chemical, 2016, 228( 2) , 673-678.
15、ShuChen, JianTang,YangfangKuang, LiliFu, FangfangMa,YuanyuanYang, GuanfanChen, etc. Selective deposition of HgS at the corner sites of triangular silver nanoprism and its tunable LSPR for colorimetric Hg2+ detection, Sensors and Actuators B: Chemical, 2015, 221(31),1182-1187
16、付秀芳,李媛媛,时统昊,陈冠凡等,一种卟啉结构硫离子荧光探针的合成及荧光性能,化学研究与应用,2019,8,1499-1504。
17、李媛媛,陈冠凡,时统昊等,取代苯及其衍生物电离能中的新取代基参数,计算机与应用化学,2019,3,265-273
18、陈冠凡,曾荣今,成奋民,烯烃离子型亲电加成反应中取代基定位规则的应用,当代教育理论与实践,2016,11,23-26
19、曹晨忠,陈冠凡,武亚新,取代基和溶剂对4,4'-二取代二苯乙烯紫外吸收能量的影响,中国科学:化学,2012,2,127-137
20、陈冠凡,曹晨忠,盛斌等,对位二取代苯电离能中取代基效应的研究, 计算机与应用化学, 2011,11, 1381-1386
主要从事(1)新型荧光探针分子的设计、合成及其识别性质的研究,(2)分子结构与性能之间构效关系(QSPR)的研究。